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Related Experiment Videos

Latex hypersensitivity: two case reports.

D J Ber1, A E Davidson, D E Klein

  • 1Division of Allergy/Immunology, Rhode Island Hospital, Providence.

Allergy Proceedings : the Official Journal of Regional and State Allergy Societies
|March 1, 1992
PubMed
Summary
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Latex hypersensitivity can cause severe allergic reactions, including anaphylaxis. Healthcare workers exposed to latex products are at increased risk, necessitating the use of latex-free alternatives.

Area of Science:

  • Allergy and Immunology
  • Occupational Health

Background:

  • Latex hypersensitivity is a growing concern, with documented cases of urticaria, asthma, and anaphylaxis linked to latex exposure since 1979.
  • Increased use of latex products in healthcare settings, particularly due to new guidelines for sexually transmitted disease prevention, heightens occupational risk.

Observation:

  • Two cases of latex hypersensitivity are presented: a 30-year-old surgeon and a 24-year-old nurse.
  • Both patients exhibited significant reactions to latex exposure, confirmed by positive skin-prick tests and elevated latex antigen-specific IgE levels (RAST).

Findings:

  • The surgeon showed a 4+ skin-prick test reaction and RAST levels 50.75 times above control.
  • The nurse displayed a 2+ skin-prick test reaction and RAST levels 23.37 times above control.

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  • Both patients received immediate treatment with epinephrine and diphenhydramine.

    • Implications:

    • Healthcare personnel require strict avoidance of latex products and use of latex-free alternatives to prevent severe allergic reactions.
    • The rising incidence of latex hypersensitivity among healthcare workers necessitates proactive management and awareness programs.