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Updated: Aug 18, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
Published on: September 8, 2023
[Change in the definition of osteoporosis especially on bone quality]
1Department of Orthopedic Surgery, Sanin Rosai Hospital.
Abstract:
In recent years the term Bone Quality has been used with increasing frequency in the field of osteoporosis diagnosis and treatment. Bone quality is an umbrella term which describes a set of characteristics that influence bone strength. The strength of bone depends on its structure and material properties which are affected by bone remodeling and modeling. The structural property is determined by the size and shape of bone and also the microarchitecture. Material property can be determined by mineral crystallinity, collagen structure and micro-damage in bone. Osteoporosis is defined as a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fracture. Bone strength reflects the integration of two main features: bone density and bone quality.
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