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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Lepromatous lymphadenitis masquerading as lymphoma
Nipin Bagla1, Mandakini M Patel, Rajnikant D Patel
1Department of Pathology, Government Medical College, Majura Gate, Surat-395001, Gujarat, India. drnipinbagla@yahoo.co.in
Leprosy Review
|May 11, 2005
Summary
Lepromatous lymphadenitis, a leprosy complication, can mimic non-Hodgkin
Area of Science:
- Medical Microbiology
- Immunopathology
- Dermatology
Background:
- Lymphadenopathy presents a diagnostic challenge, often necessitating differential diagnosis for conditions like lymphoma.
- Leprosy, a chronic infectious disease, can manifest with diverse clinical presentations, including atypical forms.
Observation:
- A 70-year-old male with generalized lymphadenopathy was initially suspected of having non-Hodgkin's lymphoma.
- Excision and histopathological examination of lymph nodes revealed lepra cells laden with Mycobacterium leprae.
Findings:
- Histopathology confirmed lepromatous lymphadenitis, characterized by aggregates of lepra cells.
- The presence of abundant lepra bacilli within the lymph node cells was a key diagnostic feature.
Implications:
- Clinicians in leprosy-endemic regions must consider lepromatous lymphadenitis in patients presenting with lymphadenopathy.
- This highlights the importance of including infectious etiologies in the differential diagnosis of lymphadenopathy, even when lymphoma is suspected.
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