Biologic perspectives to support clinical choices in root canal treatment

Some of the most keenly debated issues in endodontics have revolved around the where to end the root filling, as well as cleaning and shaping and obturation techniques. In some respects, original scientifically-based concepts have been abandoned in favour of clinical techniques that may provide aesthetically pleasing radiographs, but do not necessarily support tissue regeneration around the root apex following obturation. Recently advocated obturation techniques supporting the use of resin-based and bonded materials have not had the same extensive evaluation that gutta-percha, when in contact with the periradicular tissues, has had. Further studies are necessary so that evidence-based data can support the confident use of these innovative materials.