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Artificial and engineered chromosomes: non-integrating vectors for gene therapy

Joydeep Basu1, Huntington F Willard

  • 1Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA. joydeep.basu@duke.edu

Trends in Molecular Medicine
|May 11, 2005
PubMed
Summary

Non-integrating gene-delivery vectors show promise for gene therapy. However, challenges in composition and delivery currently limit the clinical use of artificial or engineered chromosomes.

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