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Updated: Aug 15, 2026

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
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RNA translational control in skeletal development, homeostasis, and disease

Denghao Huang1, Siyuan Hu2, Qiwen Li1

  • 1State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China; National Center for Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China; National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China; Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China.

Trends in Molecular Medicine
|August 13, 2026
PubMed
Summary

mRNA translation, the process of creating proteins, is crucial for skeletal health but poorly understood. New translatomics research reveals its role in bone development and repair, offering potential therapeutic targets for skeletal defects.

Keywords:
RNA translationbone developmentbone diseasesprotein synthesis

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