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WHI and aftermath: looking beyond the figures
1Department of Medicine T, Ichilov Medical Center, Tel-Aviv, and the Menopause Clinic, Ramat-Marpe, Ramat-Gan, 6 Weizman Street, Tel-Aviv 64239, Israel. apines@netvision.net.il
Abstract:
In contrast to the preliminary results of the WHI conjugated equine estrogen plus medroxyprogesterone acetate arm published 2 years ago, the final results from that arm as well as preliminary data from the conjugated equine estrogen-only arm showed that the panic over hormone treatment for menopausal women was unjustified. Moreover, the data for women younger than 60-years-old was even more reassuring. WHI was a study on elderly women starting hormones under the assumption that it may confer cardioprotection. The results of WHI should not be generalized and should not be a reason to withhold hormones in symptomatic perimenopausal or early post-menopausal women who could benefit from that therapy.
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