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Updated: Jul 11, 2026
09:40
Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
Published on: June 11, 2015
The third age of phage.
1Department of Biological Sciences, University of Warwick, Coventry, United Kingdom. N.H.Mann@warwick.ac.uk
Plos Biology
|May 12, 2005
Summary
The third age of phage is here, recognizing bacteriophages (phages) as crucial for planetary biogeochemical cycles. Phages represent a vast, untapped genetic resource with significant biosphere potential.
Area of Science:
- Microbiology
- Environmental Science
- Genetics
Background:
- Bacteriophages (phages) are viruses that infect bacteria.
- Their roles in microbial ecosystems are increasingly recognized.
- Phages are abundant in all biosphere environments.
Purpose of the Study:
- To highlight the significance of the "third age of phage" in scientific understanding.
- To underscore the pivotal role of phages in global biogeochemical cycles.
- To emphasize the immense genetic potential harbored by phages.
Main Methods:
- Review of current scientific literature on phage biology and ecology.
- Analysis of phage impact on microbial communities.
- Assessment of phage genetic diversity and potential applications.
Main Results:
- Phages are fundamental drivers of planetary biogeochemical cycles.
- Phages possess the largest known genetic reservoir in the biosphere.
- Understanding phage-host interactions is critical for ecosystem dynamics.
Conclusions:
- The "third age of phage" signifies a paradigm shift in microbial ecology and biotechnology.
- Phages are essential components of Earth's biogeochemical processes.
- Harnessing phage genetic resources offers unprecedented opportunities for science and industry.
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