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[Chronic meningococcemia]

D Carré1, A Dompmartin, K Sannier

  • 1Service de Dermatologie, CHR du Havre.

Annales De Dermatologie Et De Venereologie
|May 12, 2005
PubMed
Abstract

Insights

Chronic meningococcemia, a rare Neisseria meningitidis infection, presents with a rash, fever, and joint pain. Prompt antibiotic treatment is effective and confirms the diagnosis.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Dermatology

Background:

  • Chronic meningococcemia is an uncommon manifestation of invasive Neisseria meningitidis infection.
  • This condition requires careful differentiation from other diseases presenting with similar symptoms.

Observation:

  • Two cases are presented involving a 39-year-old male and a 42-year-old female.
  • Patients exhibited a widespread, transient maculopapular rash, intermittent fever, and arthralgia.
  • Leukocytoclastic vasculitis was noted on cutaneous histology.

Findings:

  • Blood cultures identified serogroup B meningococcus in both patients, confirming the diagnosis.
  • Treatment with beta-lactam antibiotics resulted in successful recovery.
  • The clinical triad of rash, fever, and arthralgia is characteristic of this septicemia.

Implications:

  • Accurate diagnosis is crucial to avoid complications from incorrect treatments like corticosteroids.
  • Blood cultures are essential for confirming meningococcemia and may require repetition.
  • Rapid clinical improvement following antibiotic administration supports the diagnosis of chronic meningococcemia.

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