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Cardiomyopathy associated with celiac disease
Nisheeth K Goel1, Robert D McBane, Patrick S Kamath
1Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA.
Mayo Clinic Proceedings
|May 13, 2005
Summary
Celiac disease, a small intestine disorder, can rarely cause cardiomyopathy. Early diagnosis and a gluten-free diet can lead to significant improvement and reversibility of cardiac function in affected individuals.
Area of Science:
- Gastroenterology and Cardiology
Background:
- Celiac disease (or celiac sprue) is an autoimmune disorder of the small intestine triggered by gluten ingestion in genetically predisposed individuals.
- It is characterized by chronic malabsorption and is associated with various conditions, but cardiomyopathy is considered rare.
Observation:
- This study details a patient diagnosed with celiac disease who also presented with cardiomyopathy.
- The patient's cardiac function showed substantial improvement following the implementation of a gluten-free diet.
Findings:
- Cardiomyopathy can be a serious, potentially fatal complication of celiac disease.
- Treatment with a gluten-free diet can lead to complete reversibility of cardiomyopathy in celiac disease patients.
Implications:
- Highlights the importance of considering celiac disease in patients with unexplained cardiomyopathy.
- Emphasizes that early diagnosis and dietary intervention can significantly improve cardiac outcomes in celiac disease.
- Suggests a potential link between celiac disease and cardiac health that warrants further investigation.