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Updated: Aug 18, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Unusual infection complication of total hip arthroplasty]
1II. Ortopedická klinika LF UK a FN Ruzinov, Bratislava. jany@nspr.sk
Abstract:
Authors present the case history of a 66-year old patient after repeated reimplantations of the THA with a deep infect caused by a rare aetiological agent (Serratia marcescens) associated with a pyogenic sinus. They describe the disease history, therapeutic procedure, complications associated with the surgery as well as postoperative course after the reimplantation of a customized total hip replacement. In the conclusion they state that in case of an infected total hip arthroplasty the treatment is focused on the salvage of the infection process and preservation of the function of the affected limb. Of essential importance is surgical revision with a radical removal of necrotic tissues and hardware in combination with an intensive parenteral antibiotic administration.
Insights
This case study details managing a deep hip infection caused by Serratia marcescens following total hip arthroplasty (THA) reimplantation. Effective treatment requires surgical revision and intensive antibiotics to preserve limb function.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Medical Microbiology
Background:
- Deep infection following total hip arthroplasty (THA) presents significant management challenges.
- Recurrent THA reimplantation increases the risk of persistent or deep-seated infections.
- Rare pathogens like Serratia marcescens require specific diagnostic and therapeutic considerations.
Observation:
- A 66-year-old patient developed a deep infection post-THA reimplantation, caused by Serratia marcescens.
- The infection was associated with a pyogenic sinus, complicating the clinical presentation.
- The patient underwent repeated reimplantations of the total hip replacement.
Findings:
- Surgical revision with radical debridement of necrotic tissue and hardware removal is critical.
- Intensive parenteral antibiotic administration is essential for eradicating the infection.
- Successful management focused on infection salvage and limb function preservation.
Implications:
- This case highlights the importance of identifying rare etiological agents in infected THA.
- Aggressive surgical and antibiotic strategies are necessary for favorable outcomes in complex cases.
- Preserving limb function is the primary goal in managing infected total hip arthroplasty.
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