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Published on: January 10, 2019
[Phlegmasia caerulea dolens: therapeutic considerations]
Pereira Albino1, D Gonçalves, G Sobrinho
1Serviço de Angiologia e Cirurgia Vascular, Hospital Pulido Valente, Lisboa.
Insights
Phlegmasia caerulea dolens, a rare deep venous thrombosis complication, requires prompt diagnosis and treatment. Early intervention improves outcomes, though results vary based on the underlying cause.
Area of Science:
- Vascular Surgery
- Hematology
- Oncology
Background:
- Phlegmasia caerulea dolens is a severe complication of deep venous thrombosis (DVT).
- It results from extensive venous outflow occlusion, leading to limb ischemia.
- Early diagnosis and intervention are critical for effective management.
Observation:
- Retrospective analysis of 3 cases treated between 2001 and 2005.
- All patients had underlying malignancies (lung or prostate cancer).
- Treatment involved venous thrombectomy and caval filter placement.
Findings:
- Two patients achieved good outcomes, with complete resolution or minor amputation.
- One patient required an above-knee amputation.
- Treatment success is influenced by diagnostic timeliness and etiology.
Implications:
- Emphasizes the importance of rapid diagnosis for phlegmasia caerulea dolens.
- Highlights venous thrombectomy as a viable treatment option.
- Underscores the prognostic impact of underlying malignancy on treatment results.
Abstract:
Phlegmasia caerulea dolens is a rare complication of a deep venous thrombosis and is the result of a massive occlusion of all venous outflow of the extremity. Diagnosis must be made early in the course of the process for treatment effectiveness although it can only produce modest results. The authors analyse retrospectively 3 cases that were treated between 2001 and 2005. The three patients suffered from malignancies (2 from lung and one fom prostate). In all patients a venous thrombectomy was performed and the method employed was described, which includes the systematic use of a caval filter. Two patients coursed with good results, with complete resolution or minor amputation. However, one patient needed an above knee amputation. The authors concluded that the time that mediate to the precise diagnosis and the best option of treatment are important determinations on the results, that however are very dependent on the etiology of this clinical situation.
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