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Spontaneous haemophilus influenzae type B meningoventriculitis with intraventricular debris

Hiroyuki Nakayasu1, Hiroaki Sawada, Mitsuru Doi

  • 1Department of Neurology, Tottori Prefectural Central Hospital, Tottori.

Internal Medicine (Tokyo, Japan)
|May 18, 2005
PubMed

Insights

This case study details the first spontaneous occurrence of Haemophilus influenzae type B meningoventriculitis. Prompt antibiotic treatment led to a full recovery without lasting neurological deficits.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Medical Case Reports

Background:

  • Meningoventriculitis, inflammation of the meninges and brain ventricles, is a severe neurological condition.
  • Haemophilus influenzae type B (Hib) is a significant cause of bacterial meningitis, particularly in unvaccinated populations.

Observation:

  • A 47-year-old male presented with fever, headache, and neck stiffness.
  • Cerebrospinal fluid (CSF) analysis revealed turbidity, Gram staining, and latex agglutination confirmed Haemophilus influenzae type B.
  • Cranial CT and MRI showed ventricular debris, periventricular hyperintensity, and ependymal enhancement.

Findings:

  • The patient was diagnosed with spontaneous Haemophilus influenzae type B meningoventriculitis.
  • Intravenous antibiotic therapy was initiated for the confirmed Hib infection.
  • Neuroimaging demonstrated a positive response to antibiotic treatment, with gradual resolution of abnormalities.

Implications:

  • This case highlights the potential for spontaneous Haemophilus influenzae type B meningoventriculitis in adults.
  • Early diagnosis and prompt antibiotic intervention are crucial for favorable outcomes.
  • Successful treatment resulted in complete patient recovery without sequelae, underscoring the efficacy of timely medical care.

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