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Related Experiment Videos

Double-chambered right ventricle in adulthood.

Mitsugi Nagashima1, Tetsuo Tomino, Harumitsu Satoh

  • 1Department of Cardiovascular Surgery, Ehime Prefectural Central Hospital, Matsuyama city, Ehime, Japan. mitsugi@aqua.plala.or.jp

Asian Cardiovascular & Thoracic Annals
|May 21, 2005
PubMed
Summary

Adults with double-chambered right ventricle (DCRV) present rarely with symptoms. Surgical correction in adults yielded satisfactory midterm results, despite severe obstruction and symptoms, with all survivors in New York Heart Association functional class I.

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Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Adult Congenital Heart Disease

Background:

  • Double-chambered right ventricle (DCRV) is a rare congenital heart defect.
  • Symptomatic presentation of DCRV in adulthood is uncommon.
  • Surgical outcomes in adults with DCRV are not well-documented.

Purpose of the Study:

  • To compare the clinical presentation and surgical outcomes of adults and children with DCRV.
  • To evaluate the efficacy of surgical correction for DCRV in adult patients.
  • To assess the midterm results of DCRV repair in adults.

Main Methods:

  • Retrospective analysis of 4 adult and 9 pediatric patients who underwent surgical correction for DCRV between 1990 and 2004.
  • Comparison of clinical data, including age at operation, presenting symptoms, and hemodynamic parameters (pressure gradient, pulmonary-to-systemic flow ratio).

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  • Evaluation of surgical outcomes, survival rates, and functional status (New York Heart Association class).

    • Main Results:

    • Adults presented with severe dyspnea on exertion, while pediatric patients had milder symptoms or were asymptomatic.
    • Adults had significantly higher right ventricular outflow tract pressure gradients and lower pulmonary-to-systemic flow ratios compared to children.
    • All adult patients and 8 of 9 children survived surgery, with no late deaths or re-operations. Survivors were in New York Heart Association functional class I.

    Conclusions:

    • Surgical correction of DCRV in adults provides satisfactory midterm results.
    • Adults with DCRV often present with more severe obstruction and symptoms than pediatric patients.
    • Despite challenges, surgical intervention for DCRV in adults leads to good functional recovery.