Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lymphocyte functions in overconditioned cows around parturition.

N Lacetera1, D Scalia, U Bernabucci

  • 1Dipartimento di Produzioni Animali, Università della Tuscia, 01100 Viterbo, Italy. nicgio@unitus.it

Journal of Dairy Science
|May 21, 2005
PubMed
Summary

Overconditioned dairy cows exhibit reduced immune function around calving, indicated by lower immunoglobulin M and interferon-gamma secretion. This highlights the impact of body condition on periparturient immune status in cattle.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic Mapping of Ruminant Milk Extracellular Vesicles using Text Mining and Topic Analysis approach.

Journal of dairy science·2026
Same author

Heat Stress Small Extracellular Vesicles Impair PMNs' Immunity in Holstein and Brown Swiss Dairy Cows.

Journal of dairy science·2026
Same author

Effects of cognitive-motor interference during walking: A meta-analysis on healthy individuals.

Neuroscience and biobehavioral reviews·2025
Same author

Establishing the African region monitoring vaccine effectiveness (AFRO-MoVE) network for respiratory pathogens.

Vaccine·2025
Same author

Application of a generalized additive mixed model in time series study of dairy cow behavior under hot summer conditions.

Journal of dairy science·2024
Same author

Effects of milk extracellular vesicles from Holstein Friesian and Brown Swiss heat-stressed dairy cows on bovine mammary epithelial cells.

Journal of dairy science·2024

Area of Science:

  • Veterinary Immunology
  • Ruminant Nutrition
  • Dairy Cattle Physiology

Background:

  • Periparturient dairy cows experience significant physiological changes.
  • Body condition score (BCS) influences metabolic status and immune function.
  • Understanding immune responses around calving is crucial for herd health.

Purpose of the Study:

  • To investigate the relationship between body condition and lymphocyte function in periparturient dairy cows.
  • To assess how BCS affects peripheral blood mononuclear cell (PBMC) function around calving.
  • To identify potential immune challenges associated with different body conditions in dairy cows.

Main Methods:

  • Categorized 21 Holstein cows into thin, medium, and overconditioned groups based on BCS before calving.

Related Experiment Videos

  • Collected blood samples at multiple time points before and after parturition.
  • Analyzed plasma nonesterified fatty acids (NEFA) and glucose, and assessed PBMC functions including DNA synthesis, IgM, and IFN-gamma secretion.

    • Main Results:

    • Overconditioned cows lost more BCS and had higher plasma NEFA post-calving compared to thin cows.
    • PBMC DNA synthesis and IgM secretion were lower before calving than after, irrespective of BCS.
    • Overconditioned cows showed reduced IgM secretion and lower IFN-gamma secretion around calving compared to thin or medium cows.

    Conclusions:

    • Immunodepression around calving is more pronounced in overconditioned dairy cows.
    • Body condition significantly impacts specific lymphocyte functions, particularly IgM and IFN-gamma secretion.
    • Managing body condition in dairy cows is essential for maintaining robust immune function during the critical periparturient period.