Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Migraine and the neck: new insights from basic data.

Thorsten Bartsch1

  • 1Department of Neurology, University of Kiel, Schittenhelmstr. 10, 24105 Kiel, Germany. t.bartsch@neurologie.uni-kiel.de

Current Pain and Headache Reports
|May 24, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intravenous immunoglobulin as first-line acute treatment in adults with autoimmune encephalitis caused by antibodies to NMDAR, LGI1 and CASPR2.

Journal of neurology·2025
Same author

Cognitive Deficits in Anti-LGI1 Encephalitis Are Linked to Immunotherapy-Resistant White Matter Network Changes.

Neurology(R) neuroimmunology & neuroinflammation·2025
Same author

Deep brain stimulation of the subthalamic nucleus restores spatial reversal learning in patients with Parkinson's disease.

Brain communications·2024
Same author

Disease- and stage-specific alterations of the oral and fecal microbiota in Alzheimer's disease.

PNAS nexus·2024
Same author

Reduced overnight memory consolidation and associated alterations in sleep spindles and slow oscillations in early Alzheimer's disease.

Neurobiology of disease·2023
Same author

[Parkinson's and Alzheimer's disease as system-wide neurodegenerative disorders].

Der Nervenarzt·2023
Same journal

A Systematic Review and Meta-Analysis of Randomized Controlled Trials of Epidural Regenerative Medicine Therapies in Managing Spinal Pain.

Current pain and headache reports·2026
Same journal

Artificial Intelligence in Neuropathic Pain: From Mechanisms to Neuromodulation and Regenerative Strategies.

Current pain and headache reports·2026
Same journal

Proposed Conditions for Pain Reprocessing Therapy Readiness: Beyond Phenotyping Neuroplastic Pain.

Current pain and headache reports·2026
Same journal

Treatment of Headache in Children and Adolescents with POTS.

Current pain and headache reports·2026
Same journal

Pediatric Headache in the Age of Social Media: A Topical Review.

Current pain and headache reports·2026
Same journal

Radiopharmaceuticals for the Treatment of Chronic Cancer Pain.

Current pain and headache reports·2026
See all related articles

Migraine pain involves complex trigemino-cervical interactions, where neck input and central sensitization contribute to pain. Understanding these mechanisms may lead to new pain-modulating therapies.

Area of Science:

  • Neuroscience
  • Pain Medicine
  • Clinical Neurology

Background:

  • Migraine pain often spreads across trigeminal and cervical areas.
  • Associated symptoms include hyperalgesia and allodynia, suggesting complex neural interactions.

Purpose of the Study:

  • To review the clinical presentation and underlying mechanisms of trigemino-cervical interaction in migraine.
  • To explore how nociceptive input from the upper cervical spine integrates into the trigemino-cervical system.

Main Methods:

  • Review of clinical presentations and physiological mechanisms.
  • Discussion of central sensitization and neuroplastic changes.
  • Analysis of nociceptive input modulation by spinal and brainstem mechanisms.

Main Results:

Related Experiment Videos

  • Clinical migraine presentation indicates dynamic trigemino-cervical interaction.
  • Physiologic mechanisms involve afferent convergence and central sensitization.
  • Neck nociception integrates into the trigemino-cervical system, modulated by segmental and brainstem pathways.

Conclusions:

  • The trigemino-cervical system plays a crucial role in migraine pathophysiology.
  • Understanding these interactions is key for developing novel pain modulation strategies.
  • Neurostimulation of afferent nerves shows promise for migraine pain management.