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Updated: Aug 17, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Bone metastases from primary hepatocellular carcinoma simulating multiple myeloma
Dinesh Chandra Doval1, Komal Bhatia, Ashok Kumar Vaid
1Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini Sector-5, Delhi 110085, India. dcdoval@yahoo.com
Abstract:
A 65-year-old man presented with bone pains and anemia. Skull X-ray revealed multiple osteolytic lesions. The patient was evaluated for multiple myeloma but detailed workup revealed the diagnosis of primary hepatocellular carcinoma (HCC) with osteolytic bone metastases. Thus, bone metastases due to HCC, although rare, should be considered in patients presenting with bone pains due to osteolytic lesions.
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