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Bone metastases from primary hepatocellular carcinoma simulating multiple myeloma
Dinesh Chandra Doval1, Komal Bhatia, Ashok Kumar Vaid
1Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini Sector-5, Delhi 110085, India. dcdoval@yahoo.com
Summary
A rare case of primary hepatocellular carcinoma (HCC) presented with bone pain and anemia. Osteolytic bone metastases from HCC, though uncommon, should be considered in differential diagnoses.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Hepatocellular carcinoma (HCC) is a primary liver cancer.
- Bone metastases are a known complication of advanced cancers.
- Osteolytic lesions are indicative of bone destruction.
Observation:
- A 65-year-old male presented with bone pain and anemia.
- Skull X-ray showed multiple osteolytic lesions.
- Initial evaluation suggested multiple myeloma.
Findings:
- Detailed workup confirmed primary hepatocellular carcinoma (HCC).
- The patient had osteolytic bone metastases originating from HCC.
- This highlights a rare presentation of HCC.
Implications:
- Consider hepatocellular carcinoma (HCC) in the differential diagnosis of unexplained osteolytic bone lesions.
- Early recognition of rare metastatic patterns can improve patient outcomes.
- This case emphasizes the importance of comprehensive diagnostic workup for bone pain.