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Updated: Aug 17, 2026

Strategies for Assessing Autistic-Like Behaviors in Mice
Published on: September 20, 2024
Autism research: lessons from the past and prospects for the future
1SGDP Centre, Institute of Psychiatry, Box P080, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK. j.wickham@iop.kcl.ac.uk
Abstract:
The paper uses both the author's experience of research training, and the empirical studies of autism in which he participated over the last 40-plus years, to derive research lessons and to consider the needs and prospects for future research. Attention is drawn to: the importance of mentors; the need to use technologies in a hypothesis-testing fashion; the important of possible creative/innovative leaps and of recognition of the unexpected; the need to ask challenging questions and to recognize when the original ideas were mistaken. There is great value in broadening the scientific strategies used to investigate a particular condition and much is to be gained by deliberately seeking parallels with other conditions.
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