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Related Experiment Videos

[Selenium: the biological role and antioxidant activity].

V A Baraboĭ, E N Shestakova

    Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
    |May 25, 2005
    PubMed
    Summary

    Selenium, an essential trace element, acts as a potent antioxidant and immunomodulator. This vital nutrient protects against various diseases, including cancer and heart disease, but requires careful dosage due to its toxicity.

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    Area of Science:

    • Biochemistry
    • Nutrition Science
    • Toxicology

    Context:

    • Selenium is a crucial trace element with significant biological roles.
    • It functions as a sulfur analogue with high chemical reactivity.
    • It is a component of vital selenoproteins and enzymes, such as glutathione peroxidase.

    Purpose:

    • To elucidate the multifaceted biological functions and health impacts of selenium.
    • To highlight its antioxidant and immunomodulatory properties.
    • To discuss its role in thyroid hormone biosynthesis and protection against chronic diseases.

    Summary:

    • Selenium and its compounds exhibit potent antioxidant activity, surpassing vitamins E, C, A, and beta-carotene.
    • It plays a critical role in thyroid hormone conversion and protects sperm motility and fertility.
    • Selenium is essential for the biological and antioxidant protection of vascular endothelium, lipoproteins, DNA, and chromosomes.

    Impact:

    • Dietary selenium intake is linked to protection against atherosclerosis, coronary ischemic disease, and cancer.
    • It is recognized as a potent immunomodulator.
    • Understanding selenium's dual role as essential nutrient and potential toxin is crucial for health and disease prevention.

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