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[Evaluation of left ventricular function with a 16-slice multidetector tomograph (MDCT-16): correlation with
Erasmo de la Peña-Almaguer1, José Ramón Azpiri López, Felipe de Jesús González-Camid
1Departamento de Imagenología Cardiovascular, Hospital Christus-Muguerza de Monterrey, Hidalgo 2525 Pte, col. Obispado, Monterrey, NL 64040. erasmo@bwh.harvard.edu
Insights
Multidetector computed tomography (MDCT-16) accurately assesses left ventricular function, correlating well with MRI. This non-invasive method provides reliable data for evaluating cardiac function alongside coronary anatomy.
Area of Science:
- Cardiovascular imaging
- Diagnostic radiology
- Cardiac function assessment
Context:
- Left ventricular function evaluation is crucial for prognostic and therapeutic decisions in heart disease patients.
- Non-invasive coronary angiography with 16-slice multidetector computed tomography (MDCT-16) offers high spatial and temporal resolution for cardiac imaging.
- MDCT-16 can provide data on left ventricular function in addition to coronary anatomy.
Purpose:
- To correlate left ventricular function parameters obtained by MDCT-16 with Magnetic Resonance Imaging (MRI) as the reference standard.
- To assess the utility of MDCT-16 in evaluating key left ventricular functional metrics.
Summary:
- Twenty patients (18 males, mean age 52±15 years) underwent evaluation using both MDCT-16 and MRI.
- No significant differences were observed between MDCT-16 and MRI measurements for end-diastolic volume, end-systolic volume, stroke volume, left ventricular mass, and left ventricular ejection fraction.
- Statistical analysis revealed a high correlation between the two imaging modalities for clinically relevant ventricular function parameters.
Impact:
- MDCT-16 demonstrates high accuracy in assessing left ventricular function, comparable to MRI.
- This suggests that MDCT-16 is a valuable tool for simultaneously evaluating coronary anatomy and left ventricular function non-invasively.
- Findings support the integration of MDCT-16 into clinical practice for comprehensive cardiac assessment.
Unlabelled:
The evaluation of Left ventricular function has both prognostic as well as therapeutic implications in patients with heart disease. Non-invasive coronary angiography with computed tomography using 16 slices (MDCT-16) allows to obtain images of the coronary anatomy due to its high spatial and temporal resolution, and also, to obtain data regarding Left ventricular function. The objective of this study was to correlate the use of MDCT-16 for the evaluation of the Left ventricular parameters using MRI as the Standard of reference.
Methods:
MRI: Se A 1.5 Tesla GE CvI Scanner optimized for cardiovascular applications was used. Using an ECG gated steady state fast precession sequence (SSFP, Thickness 10 mm, Flip Angle 45, FOV 36 cm. NEX 1, Frequency 256, Phase 128, Partial FOV 0.75, 16VPS), 6 to 8 short axis images of from base to apex of the left ventricle were obtained. Tomography: Using a 16 slice Multidetector tomograph (GE Lightspeed) and using ECG synchronization, images of the heart were obtained after the administration of 80 mls. of no-ionic contrast. The images were reconstructed off-line to obtain from 6 to 8 slices in a similar fashion to that of MR. Both studies were independently analyzed by 2 operators who obtained the ventricular function data. Linear correlation and a Paired T Student test was used to analyze the data and was considered significant when p < 0.05.
Results:
20 consecutive patients were evaluated with MDCT-16 and MRI, 18 males, mean age 52 +/- 15 years. There was no significant difference among the measurements for cardiac CT and MRI of the end-diastolic volume (EDV) and end-sistolic volume (ESV), stroke volume (SV), LV Mass or LV ejection fraction (LVEF).
Conclusion:
This results show a high correlation among the clinically relevant ventricular function parameters evaluated by cardiovascular CT and MRI. This findings suggest that ventricular function can be successfully evaluated along with the coronary anatomy using MDCT-16.
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