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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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Published on: October 28, 2020

[Left ventricle dilatational lesion. Problems of nosology, diagnostics, and treatment]

L A Bokeriia, I I Skopin, E Z Golukhova

    Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
    |May 25, 2005
    PubMed

    Insights

    The WHO's term "specific cardiomyopathy" may not accurately describe advanced left ventricle issues in heart valve disease. A proposed classification better categorizes patients for improved research into left ventricle dilatation.

    Area of Science:

    • Cardiology
    • Pathology

    Background:

    • The World Health Organization (WHO) adopted the term "specific cardiomyopathy" in 1995.
    • Patients with valvular heart defects often present with advanced left ventricle lesions.
    • The group of patients with dilated left ventricle cavity due to acquired heart diseases is heterogeneous, comprising approximately 50% of surgical patients.

    Purpose of the Study:

    • To address the limitations of the term "specific cardiomyopathy" in describing left ventricle lesions in valvular heart disease.
    • To propose a more refined classification of left ventricle dilatation in patients with valvular heart defects.
    • To facilitate further research into the pathophysiology and management of left ventricle dilatation in this patient group.

    Main Methods:

    • Retrospective analysis of patient data with valvular heart defects and left ventricle dilatation.
    • Clinical and pathological evaluation to differentiate subgroups of left ventricle dilatation.
    • Review of existing literature and WHO classifications.

    Main Results:

    • The current term "specific cardiomyopathy" is considered inadequate for advanced left ventricle lesions in valvular heart disease.
    • A proposed classification divides patients into three main subgroups: 1) quickly regressing symptomatic dilatation from volume overload, 2) valvular cardiomyopathy (terminal stage), and 3) intermediate stage dilatational lesion with pathological remodeling and segmental contractility disturbance.
    • This stratification is deemed beneficial for future investigations.

    Conclusions:

    • The classification of left ventricle dilatation in valvular heart disease requires refinement beyond the current "specific cardiomyopathy" terminology.
    • A proposed three-subgroup division offers a more precise framework for understanding and studying these complex cardiac conditions.
    • This approach supports targeted research and potentially improved patient management strategies.

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