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Related Experiment Videos

Acceptability of five nonoxynol-9 spermicides.

Elizabeth G Raymond1, Pai Lien Chen, Sean Condon

  • 1Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA. eraymond@fhi.org

Contraception
|May 26, 2005
PubMed
Summary

Most users found nonoxynol-9 (N-9) spermicides acceptable, with gels being more preferred than films or suppositories. Acceptability did not impact spermicide use or pregnancy risk.

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Area of Science:

  • Reproductive Health
  • Contraception Research
  • Clinical Trials

Background:

  • Nonoxynol-9 (N-9) is a common spermicide.
  • Understanding user acceptability is crucial for contraceptive method effectiveness.

Purpose of the Study:

  • To evaluate the acceptability of five different N-9 spermicides.
  • To determine if spermicide acceptability influences usage or pregnancy risk.

Main Methods:

  • Analysis of data from a randomized trial involving 1536 participants.
  • Participants used assigned N-9 spermicides (gels, film, suppository) for 7 months.
  • Questionnaires assessed acceptability at 4 weeks and discontinuation.

Main Results:

  • 43% of participants reported liking their spermicide "very much."

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  • Gels showed higher acceptability than suppositories and films.
  • Common complaints included insertion difficulty, messiness, and timing issues.
  • Acceptability was not linked to duration/consistency of use or time to pregnancy.

    • Conclusions:

    • All five N-9 spermicides were acceptable to most users.
    • User acceptability did not significantly affect spermicide use patterns or pregnancy risk.