Related Experiment Video
Updated: Aug 8, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
[Computer-based system for monitoring the course of intraocular inflammation]
1Interdisziplinäres Uveitiszentrum, Ruprecht-Karls-Universität Heidelberg.
Background:
Until now, there has been no consistent rating system for changes of intraocular inflammation. We present such a computer-based system.
Methods:
This program is based on a FileMaker database. It is made of anterior and posterior uveitis scores on the basis of published evaluation guidelines of the International Ocular Inflammation Society (IOIS). An anterior uveitis score consisting of anterior chamber cells, flare, and perilimbal injection on the one hand and a posterior uveitis score consisting of vitreous haze, macula, and optic nerve head edema on the other hand are calculated. After adding visual acuity, intraocular pressure, and systemic dose of corticosteroids, all parameters can be visualized by a radar graph.
Results:
This system of documentation is easy to handle and presents a simplified version of the disease course. The abstract visualization enables the patient to better understand the therapeutic management.
Conclusions:
The program presented here offers good opportunities for standardized monitoring of the disease course.

