Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

CLUSTAL V: improved software for multiple sequence alignment.

D G Higgins1, A J Bleasby, R Fuchs

  • 1European Molecular Biology Laboratory, Heidelberg, FRG.

Computer Applications in the Biosciences : CABIOS
|April 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Streamlining Global Germplasm Exchange: Integrating Scientific Rigor and Common Sense to Exclude Phantom Agents from Regulation.

Plant disease·2025
Same author

Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants.

Leukemia·2017
Same author

Loss of serum response factor induces microRNA-mediated apoptosis in intestinal smooth muscle cells.

Cell death & disease·2015
Same author

Lagrangian Coherent Structures for Design Analysis of Revolving Doors.

IEEE transactions on visualization and computer graphics·2015
Same author

Ultra-endurance exercise induces stress and inflammation and affects circulating hematopoietic progenitor cell function.

Scandinavian journal of medicine & science in sports·2014
Same author

Immunodominant proteins of Borrelia burgdorferi, the etiological agent of lyme borreliosis.

World journal of microbiology & biotechnology·2014
Same journal

DCA: an efficient implementation of the divide-and-conquer approach to simultaneous multiple sequence alignment.

Computer applications in the biosciences : CABIOS·1998
Same journal

Two applications to facilitate the viewing of database search result files on the Macintosh.

Computer applications in the biosciences : CABIOS·1998
Same journal

BioWish: a molecular biology command extension to Tcl/Tk.

Computer applications in the biosciences : CABIOS·1998
Same journal

The Sequence Alerting Server--a new WEB server.

Computer applications in the biosciences : CABIOS·1998
Same journal

A software tool for the analysis of mass spectrometric disulfide mapping experiments.

Computer applications in the biosciences : CABIOS·1998
Same journal

SAMBA: hardware accelerator for biological sequence comparison.

Computer applications in the biosciences : CABIOS·1998
See all related articles

The CLUSTAL V software offers enhanced multiple sequence alignment capabilities with new features for storing alignments and calculating phylogenetic trees. This user-friendly, menu-driven program is accessible on standard C compilers.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Evolution

Background:

  • Multiple sequence alignment is crucial for understanding protein and nucleic acid sequence relationships.
  • Existing alignment tools often lack integrated phylogenetic analysis or user-friendly interfaces.

Purpose of the Study:

  • To introduce CLUSTAL V, a rewritten and enhanced multiple sequence alignment software.
  • To highlight new functionalities including alignment storage and phylogenetic tree calculation.

Main Methods:

  • The CLUSTAL package was redeveloped into a single C program, CLUSTAL V.
  • The software features a menu-driven interface with online help for ease of use.

Main Results:

  • CLUSTAL V provides a comprehensive solution for multiple sequence alignment.

Related Experiment Videos

  • New features allow users to store and retrieve previous alignments.
  • Phylogenetic trees can be generated directly from aligned sequences.

    • Conclusions:

    • CLUSTAL V represents a significant advancement in multiple sequence alignment tools.
    • Its enhanced features and user-friendly design facilitate research in bioinformatics and evolutionary studies.