Related Experiment Videos
The effects of milacemide on item and source memory
B L Schwartz1, S Hashtroudi, R L Herting
1Washington, D.C. Veterans Affairs Medical Center 20422.
Clinical Neuropharmacology
|April 1, 1992
Summary
Milacemide, a glycine derivative, improved source memory but not item memory in adults. This suggests a dissociation between memory types, with potential implications for cognitive aging research.
Area of Science:
- Cognitive Neuroscience
- Neuropharmacology
Background:
- Item memory and source memory are distinct memory processes.
- Previous research indicates these memory types can be dissociated.
- Glycine derivatives are being investigated for their effects on cognition.
Purpose of the Study:
- To investigate the effects of milacemide on item and source memory.
- To examine these effects in both young and older adults.
- To explore potential dissociations between item and source memory under milacemide.
Main Methods:
- Administration of milacemide, a glycine derivative.
- Assessment of item memory (recognition memory).
- Assessment of source memory in healthy young and older adults.
Main Results:
- Milacemide facilitated memory for source information.
- Milacemide did not significantly affect recognition memory (item memory).
- A dissociation between source and item memory was observed.
Conclusions:
- Milacemide selectively enhances source memory.
- The findings support a dissociation between item and source memory processes.
- Milacemide may be a potential agent for modulating specific memory functions.