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[Emergence of type 2 diabetes in French children]
Paul Czernichow1, Nadia Tubiana-Rufi
1Hôpital Robert Debré, Service d'Endocrinologie, 48 boulevard Sérurier 75019 Paris.
Insights
Type 2 diabetes in children is emerging in France, though still less common than in the US. Rising childhood obesity may increase its incidence, mirroring North American trends.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Context:
- Diabetes mellitus (DM) heterogeneity is recognized, impacting disease management.
- Pediatric diabetes cases require precise classification for effective treatment and research.
- Childhood obesity is a growing concern globally, including in France.
Purpose:
- To determine the distribution of diabetes mellitus patterns in a pediatric cohort using American Diabetes Association (ADA) criteria.
- To document the emergence and incidence of type 2 diabetes mellitus in French children.
- To compare pediatric type 2 diabetes mellitus trends in France over time and with international data.
Summary:
- A review of pediatric diabetes cases (1993-1998 and 2001) in a French center used ADA criteria.
- Type 2 diabetes mellitus was diagnosed in 8 of 370 children (1993-1998) and 5 of 90 children (2001).
- While incidence remains low, a slight increase in pediatric type 2 diabetes mellitus was observed, often associated with significant obesity.
Impact:
- The study highlights the low but potentially increasing incidence of type 2 diabetes mellitus in French children.
- Findings suggest that rising childhood obesity rates in France could lead to increased type 2 diabetes mellitus cases.
- Data provides a benchmark for monitoring pediatric diabetes trends and informing public health strategies in France.
Abstract:
Increasing awareness of the heterogeneity of diabetes mellitus (DM) at presentation is changing our approach to this disease. We used the American Diabetes Association (ADA) criteria to determine the distribution of DM patterns in a large pediatric cohort, with the aim of documenting the emergence of type 2 diabetes mellitus. Charts of diabetic children aged 1 to 16 years and admitted to our center between 1993 and 1998 were reviewed for data needed to classify the type of diabetes mellitus. They were compared with the charts of diabetic children admitted to our center in 2001. During the first period, 370 children were admitted for diabetes, and type 2 diabetes was diagnosed in 8 cases. In 2001, 90 children were admitted for diabetes, of whom 5 were diagnosed with type 2 diabetes. The incidence of type 2 diabetes in France remains relatively low. Even though our data seem to indicate a slight increase, they are far below the figures reported by American pediatricians. However, cases in France are marked by major obesity. With the increase in childhood obesity in France, the incidence of type 2 diabetes may eventually rise to North American levels.
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