Related Experiment Video
Updated: Aug 17, 2026

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Pulmonary autograft for mitral valve replacement in infants: the Ross-Kabbani operation
Alessandro Frigiola1, Toni Badia, Giuseppe Pomè
1Centro Cardiovascolare Malan, Istituto Policlinico San Donato, San Donato Milanese, Italy. alfrigio@tin.it
Insights
The Ross-Kabbani procedure using a pulmonary autograft successfully treated severe mitral valve dysplasia in two infants. This surgical approach offered a viable solution for critical heart failure in very young patients.
Area of Science:
- Cardiology
- Pediatric Cardiac Surgery
- Valvular Heart Disease
Background:
- Infants with severe mitral valve dysplasia often present with critical heart failure, necessitating surgical intervention.
- Traditional surgical options like repair or mechanical prosthesis implantation are frequently unsuitable for very young infants due to anatomical limitations and anticoagulation challenges.
Observation:
- Two infants, aged 6 and 2.5 months, presented with severe mitral valve dysplasia, leading to significant valvular insufficiency and heart failure.
- The specific anatomical features of their mitral valves precluded repair, and mechanical prostheses were contraindicated due to age and anticoagulation concerns.
Findings:
- A Ross-Kabbani intervention, involving pulmonary autograft implantation in the mitral position and a pulmonary homograft, was performed in both infants.
- Both patients experienced a postoperative course free of major complications.
- Short-term follow-up demonstrated good function of the pulmonary autograft in the mitral position.
Implications:
- The Ross-Kabbani procedure with a pulmonary autograft represents a promising surgical strategy for managing severe mitral valve dysplasia in infants when other options are not feasible.
- This technique may offer a durable solution, avoiding the long-term complications associated with mechanical valves in pediatric populations.
- Further research and long-term follow-up are warranted to fully assess the durability and efficacy of this approach in pediatric valvular heart disease.
Abstract:
We describe the cases of 2 infants aged 6 and 2 1/2 months, respectively, affected by mitral valve dysplasia that caused severe valvular insufficiency and heart failure in which a surgical correction was indicated because of critical general conditions. In both patients the anatomic characteristics of the valves were not suitable for repair, and an implant of a mechanical prosthesis was excluded because of the very young age of the infants and the impossibility of maintaining an adequate anticoagulant therapy. Therefore a Ross-Kabbani intervention was performed with an implant of a pulmonary autograft (in the mitral position) and an insertion of a pulmonary homograft. The postoperative course was free of major complications and good function of the autograft was present at short-term follow-up in both cases.
More Related Videos
05:31Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
Published on: April 24, 2017