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Updated: Jul 13, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
Vacuum extraction and herpes simplex virus infection
1Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Sackler Medical School, P.O. Box 5, Holon 58100, Tel-Aviv University, Israel.
Objective:
To search for an association between delivery by vacuum extraction and an increased neonatal risk for herpes simplex virus (HSV) infection.
Methods:
In a cross-sectional, descriptive, controlled study, the study (vacuum extraction) and control (spontaneous delivery) groups each included 50 consecutive women with no history of HSV infection. Cultures for HSV were obtained from the genital tracts of all parturient women and the scalps of their newborns.
Results:
Following operative vaginal delivery, two newborns (4%) had scalp vesicles and cultures were positive for HSV for both mothers and newborns; two newborns (4%) had scalp vesicles and cultures were negative for HSV; and two newborns (4%) without scalp vesicles had cultures positive for HSV. Following spontaneous delivery, cultures were positive for HSV for four women and their newborns (8%).
Conclusion:
Herpes simplex virus isolated from the scalps of newborns may often result from colonization rather than infection.
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