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Updated: Jul 13, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

Vacuum extraction and herpes simplex virus infection.

O Sadan¹, M Dishi, E Somekh

¹Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Sackler Medical School, P.O. Box 5, Holon 58100, Tel-Aviv University, Israel.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics

|May 28, 2005

Summary

Vacuum extraction delivery showed no increased risk of neonatal herpes simplex virus (HSV) infection. HSV on newborn scalps may be colonization, not infection, regardless of delivery method.

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Area of Science:

Obstetrics and Gynecology
Neonatal Infectious Diseases
Virology

Background:

Herpes simplex virus (HSV) poses potential risks to newborns.
The association between operative vaginal delivery, specifically vacuum extraction, and neonatal HSV infection requires clarification.

Purpose of the Study:

To investigate a potential link between vacuum extraction delivery and an elevated risk of neonatal herpes simplex virus (HSV) infection.

Main Methods:

A cross-sectional, descriptive, controlled study compared 50 women undergoing vacuum extraction with 50 undergoing spontaneous delivery.
Maternal genital and neonatal scalp cultures for HSV were performed on all participants.

Main Results:

In the vacuum extraction group, 4% of newborns had positive HSV cultures (2 with vesicles, 2 without).
In the spontaneous delivery group, 8% of mothers and newborns had positive HSV cultures.
No significant difference in HSV positivity was observed between the two delivery groups.

Conclusions:

Herpes simplex virus detected on newborn scalps may frequently represent colonization rather than active infection.
Vacuum extraction delivery does not appear to increase the risk of neonatal HSV infection.