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Updated: Aug 17, 2026

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model
Published on: February 17, 2019
[Chemoradiotherapy for neurohypophyseal immature teratoma]
Yoshio Monzen1, Tomoaki Okimoto, Yoshihiro Imafuku
1Department of Radiology, Hiroshima Prefectural Hospital.
Abstract:
We performed chemoradiotherapy for two patients (aged 6 and 33 years)with neurohypophyseal immature teratoma. The patients received total doses of 40 to 50.6 Gy with concurrent carboplatin and etoposide. In both cases, neurological symptoms improved. Both patients are still alive and remain free from local recurrence and distant metastasis 92 months and 62 months, respectively, after the completion of chemoradiotherapy. No late complications were observed. Chemoradiotherapy is extremely effective in the treatment of neurohypophyseal immature teratoma.

