Related Experiment Video
Updated: Aug 17, 2026

HeLa Based Cell Free Expression Systems for Expression of Plasmodium Rhoptry Proteins
Published on: June 10, 2015
Rhomboid-like proteins in Apicomplexa: phylogeny and nomenclature
Timothy J Dowse1, Dominique Soldati
1Department of Biological Sciences, Sir Alexander Fleming Building, Imperial College London, UK, SW7 2AZ.
Abstract:
Rhomboids form a family of polytopic intramembrane serine proteases. In Toxoplasma gondii, an essential activity called microneme protein protease 1 (MPP1) cleaves secreted adhesive proteins within their transmembrane domains, at a site conserved in similar proteins of other Apicomplexa. Current evidence suggests that MPP1 is ubiquitous in the phylum and is encoded by a rhomboid gene. In this article, we present the current repertoire of rhomboid-like proteins in Apicomplexa using a nomenclature based on phylogenetic analyses.
More Related Videos
Related Concept Videos
Diversity of Protists III
Diversity of Protists II
Protein Families
Rab Proteins
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...
Diversity of Protists IV
Conservation of Protein Domains Over Different Proteins
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to form...

