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Total synthesis of syringalide B, a phenylpropanoid glycoside
1Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Health Sciences Center, Beijing 100083, PR China.
Abstract:
The first total synthesis of syringalide B, 2-(4-hydroxyphenyl)ethyl 4-O-[(E)-feruloyl]-beta-D-glucopyranoside, is described. The hydroxyl groups were protected with allyloxycarbonyl (Aoc) and allyl groups, which successfully prevent the migration of the feruloyl group during the deblocking procedure.
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