Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Drosophila shell game: patterning genes and morphological change.

Celeste A Berg1

  • 1Department of Genome Sciences, University of Washington, Box 357730, Seattle, WA 98195-7730, USA. berg@gs.washington.edu

Trends in Genetics : TIG
|June 1, 2005
PubMed
Summary

Investigating Drosophila eggshell formation reveals how cell fate decisions drive tissue morphogenesis. This study details the genetic and molecular mechanisms behind tubulogenesis, linking cell patterning to the creation of biological structures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CO2 exposure drives a rapid pH response in live adult Drosophila.

PloS one·2024
Same author

Imaginal disk growth factors are Drosophila chitinase-like proteins with roles in morphogenesis and CO2 response.

Genetics·2022
Same author

Detecting New Allies: Modifier Screen Identifies a Genetic Interaction Between <i>Imaginal disc growth factor 3</i> and <i>combover</i>, a Rho-kinase Substrate, During Dorsal Appendage Tube Formation in <i>Drosophila</i>.

G3 (Bethesda, Md.)·2020
Same author

Two Drosophilids exhibit distinct EGF pathway patterns in oogenesis.

Development genes and evolution·2017
Same author

Epithelial Patterning, Morphogenesis, and Evolution: Drosophila Eggshell as a Model.

Developmental cell·2017
Same author

Proteomics Analysis Identifies Orthologs of Human Chitinase-Like Proteins as Inducers of Tube Morphogenesis Defects in <i>Drosophila melanogaster</i>.

Genetics·2017

Area of Science:

  • Developmental Biology
  • Cell Biology
  • Genetics

Background:

  • Understanding how cell-fate information dictates tissue and organ formation is crucial in developmental biology.
  • The Drosophila eggshell provides a model system to study the link between patterning and morphogenesis.
  • Previous research established key signaling pathways specifying cell fates in the follicular epithelium.

Purpose of the Study:

  • To review the mechanisms linking cell-fate specification to morphogenetic events during Drosophila dorsal appendage formation.
  • To elucidate the processes of tubulogenesis in creating the eggshell structures.

Main Methods:

  • Analysis of genetic mutants affecting Drosophila eggshell development.
  • Molecular and cellular analyses of signaling events and cell behaviors.

Related Experiment Videos

  • Review of existing literature on patterning and morphogenesis in this system.

    • Main Results:

    • Identified combinatorial signaling events specifying dorsal anterior cell fates.
    • Detailed the morphogenetic steps converting a flat epithelium into two tubes.
    • Established the role of these tubes in forming respiratory appendages.

    Conclusions:

    • Mutant analyses provide insights into the interplay between patterning and morphogenesis.
    • The Drosophila eggshell system effectively demonstrates how cell-fate decisions translate into biological form.
    • Further research can build upon these findings to understand broader principles of organogenesis.