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Recruiting donors for autopsy based cancer research
J Thombs1, N J Borthwick, J L Hungerford
1Ocular Oncology Service, Moorfields Eye Hospital, London, UK.
Journal of Medical Ethics
|June 1, 2005
Summary
Recruiting patients for scientific research, especially for uveal melanoma studies, requires a sensitive approach. This study achieved an 88.5% recruitment rate by using personal contact and involving family, greatly exceeding the average.
Area of Science:
- Oncology
- Medical Research Ethics
Background:
- Patient recruitment is critical for study funding and success.
- Human tissue research requires sensitive and effective recruitment strategies.
- Uveal melanoma research faces challenges in patient recruitment.
Purpose of the Study:
- To investigate tumor latency in uveal melanoma using postmortem tissue.
- To evaluate effective and sympathetic patient recruitment methods for this sensitive study.
Main Methods:
- Direct patient approach during clinic visits.
- Indirect approach via mail followed by telephone contact.
- Inclusion of next of kin in the recruitment process.
Main Results:
- Achieved an 88.5% patient recruitment take-up rate in the first year.
- This rate significantly surpasses the National Institute for Clinical Excellence (NICE) average of 40%.
Conclusions:
- A sympathetic, personal approach by experienced oncology nurses is key.
- Providing clear information and involving family members enhances recruitment.
- Effective recruitment strategies are vital for the success of sensitive research studies.