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[Pain in Parkinson's disease].
R Giuffrida1, F J G Vingerhoets, J Bogousslavsky
1Service de Neurologie, CHUV, Lausanne, Suisse.
Revue Neurologique
|June 1, 2005
Summary
Two-thirds of Parkinson's disease patients experience pain, primarily muscular, osteoarticular, or neurogenic. Pain can occur early and is often linked to motor fluctuations, especially in the "off" phase.
Area of Science:
- Neurology
- Pain Medicine
- Movement Disorders
Context:
- Parkinson's disease (PD) pain is complex and poorly understood.
- Pain can be an early symptom or arise during motor fluctuations.
- Characterizing PD pain is crucial for effective management.
Purpose:
- To clinically characterize painful presentations in Parkinson's disease.
- To investigate the relationship between pain, disease stage, and motor fluctuations.
- To understand the connection between pain and PD treatment.
Summary:
- A study of 388 Parkinson's disease patients found 67% experienced pain.
- Muscular pain (stiffness, cramps) was most common (94%), followed by osteoarticular (51%) and neurogenic pain (8%).
- Pain occurred in early disease stages for a quarter of patients and was linked to motor fluctuations in a third, predominantly during "off" periods.
Impact:
- Identifies the high prevalence and common types of pain in Parkinson's disease.
- Highlights the significant association between pain and motor fluctuations in PD.
- Provides a foundation for improved diagnosis and targeted pain management strategies in Parkinson's disease patients.