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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
[Lethal course of rotavirus gastroenteritis - a case history.]
Lumír Sasek1, Petr Pazdiora, Jirí Kobr
1Children Clinic, Hospital Of Plzen, Czech Republic.
Insights
A severe case of rotaviral gastroenteritis led to fatal outcomes in an infant. Prompt medical intervention was insufficient to prevent multiorgan failure and death from this common childhood virus.
Area of Science:
- Pediatrics
- Infectious Diseases
- Gastroenterology
Background:
- Rotaviral gastroenteritis is a significant cause of severe diarrhea in infants worldwide.
- While often self-limiting, rotavirus infections can lead to severe dehydration and complications.
Purpose of the Study:
- To describe a fatal case of rotaviral gastroenteritis in an eight-month-old boy.
- To highlight the potential for severe, life-threatening complications from rotavirus infection.
Main Methods:
- Case report detailing the clinical course of an infant with rotaviral gastroenteritis.
- Postmortem stool specimen analysis confirmed rotavirus presence.
Main Results:
- The patient presented with hyperosmolar dehydration progressing to hypovolemic shock.
- Despite resuscitation and life support, the infant developed multiorgan failure including ARDS, renal failure, and DIC.
- Rotavirus was confirmed as the causative agent postmortem.
Conclusions:
- Rotaviral gastroenteritis can have a fatal course in infants, even with intensive medical care.
- This case underscores the importance of recognizing and managing severe dehydration in pediatric rotavirus infections.
Abstract:
The case of fatal course of rotaviral gastroenteritis at eight months old boy has been described. Two days history of frequent watery stools in home care, hyperosmolar dehydration grading to hypovolemic shock, cardiopulmonary resuscitation in regional hospital, transported comatose with vital functions support. In spite of temporary stabilization of the patient, there was retrogression to multiorgan failure (ischemic myocardial infliction, circulatory failure, ARDS, renal failure, DIC, enteritis, post ischemic hepatopathy). Four day later patient exits. Rotaviruses have been proved from stools specimen post mortem.
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