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LC-MS characterization of trace impurities contained in calcium folinate

Giancarlo Francese1, Federica Corana, Olivia Meneghetti

  • 1R and D Division, Cerbios-Pharma SA, via Pian Scairolo 6, CH-6917 Barbengo, Switzerland. giancarlofrancese@hotmail.com

Journal of Pharmaceutical and Biomedical Analysis
|June 2, 2005
PubMed

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Qualitative Analysis03:46

Qualitative Analysis

For solutions containing mixtures of different cations, the identity of each cation can be determined by qualitative analysis. This technique involves a series of selective precipitations with different chemical reagents, each reaction producing a characteristic precipitate for a specific group of cations. Metal ions within a group are further separated by varying the pH, heating the mixture to redissolve a precipitate, or adding other reagents to form complex ions.
For instance, group IV...