Related Experiment Video
Updated: Aug 17, 2026

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration
Published on: May 24, 2016
Myocardial protection during neonatal cardiac surgery
Madan Mohan Maddali1, John Valliattu, Jutta Fahr
1Royal Hospital, Muscat, Oman. madan@omantel.net.com
Abstract:
Myocardial protection is of major concern in neonatal cardiac surgery where coronary ostial transfer is required as part of the surgical procedure. Retrograde coronary sinus perfusion (RCSP) of cold cardioplegic solution was evaluated in infants undergoing arterial switch operations. Hemodynamic measurements and postoperative cardiac troponin I (cTnI) levels were estimated in addition to transthoracic echocardiography to assess the extent of myocardial injury. The results were compared with a similar cohort of patients where ante grade selective coronary artery perfusion (ASCP) was used during coronary ostial transfer. Our experience suggests that RCSP is a useful option in this subset of patients.

