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Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides
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Published on: June 19, 2012

Human full-length Securin is a natively unfolded protein

Nuria Sánchez-Puig1, Dmitry B Veprintsev, Alan R Fersht

  • 1Centre for Protein Engineering, Medical Research Council, Hills Road CB2 2QH, Cambridge, UK.

Protein Science : a Publication of the Protein Society
|June 3, 2005
PubMed
Summary

Human Securin (PTTG1) is a natively unfolded protein lacking stable structure. Biophysical studies found no direct interaction between Securin and the p53 tumor suppressor protein in vitro.

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