Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Bone structure and bone quality].

Teruki Sone1

  • 1Department of Nuclear Medicine, Kawasaki Medical School.

Clinical Calcium
|June 3, 2005
PubMed
Summary
This summary is machine-generated.

Bone strength depends on density and structure. Understanding bone quality, including architecture, is crucial for predicting fractures and improving non-invasive assessment methods.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of 3D-DXA-derived proximal femur measurements against QCT across international clinical cohorts.

Bone·2026
Same author

Effects of two exercise modalities and subsequent detraining on trabecular bone microarchitecture in growing male rats.

Physiological reports·2026
Same author

Correction: Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study.

Journal of bone and mineral metabolism·2024
Same author

The effects of abaloparatide on hip geometry and biomechanical properties in Japanese osteoporotic patients assessed using DXA-based hip structural analysis: results of the Japanese phase 3 ACTIVE-J trial.

Archives of osteoporosis·2023
Same author

Abaloparatide dose-dependently increases bone mineral density in postmenopausal women with osteoporosis: a phase 2 study.

Journal of bone and mineral metabolism·2023
Same author

Effect of Bone Resorption Inhibitors on Serum Cholesterol Level and Fracture Risk in Osteoporosis: Randomized Comparative Study Between Minodronic Acid and Raloxifene.

Calcified tissue international·2023

Area of Science:

  • Orthopedics and Biomedical Engineering
  • Skeletal Biology and Physiology

Context:

  • Bone strength is a complex trait influenced by multiple factors.
  • Current methods for assessing bone health primarily focus on bone mineral density.
  • The role of bone structure and material properties (bone quality) in fracture etiology is not fully understood.

Purpose:

  • To highlight the importance of bone structure and material properties in determining bone strength.
  • To emphasize the need for improved in vivo methods for evaluating bone quality.
  • To underscore the limitations of current bone density measurements in predicting fractures.

Summary:

  • Bone strength is determined by bone mineral density, geometry, microarchitecture, and material quality.
  • Including structural parameters significantly enhances bone strength prediction.

Related Experiment Videos

  • The relative contribution of bone density versus architecture to fracture risk (bone quality) requires further investigation.

    • Impact:

    • Advances in understanding bone quality can lead to more accurate fracture risk assessment.
    • Development of novel non-invasive techniques for evaluating bone quality is a key future challenge.
    • Improved assessment of bone quality could revolutionize osteoporosis diagnosis and treatment.