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Stereological and Flow Cytometry Characterization of Leukocyte Subpopulations in Models of Transient or Permanent Cerebral Ischemia
Published on: December 28, 2014
Marked cerebrospinal fluid pleocytosis in systemic lupus erythematosus related cerebral ischemia
J Abialmouna1, D W Shoemaker, P M Pullicino
1Department of Medicine, Erie County Medical Center, Buffalo, NY.
Abstract:
Pleocytosis of the cerebrospinal fluid (CSF) may accompany central nervous system lesions that occur as a result of systemic lupus erythematosus (SLE); however, the number of CSF white blood cells is usually less than 50/mm3 and the predominant cell is the lymphocyte. A young woman with SLE had 2 acute episodes of hemorrhagic cerebral ischemia, each of which was associated with a neutrophilic CSF pleocytosis (white blood count 480-2250/mm3). This type of meningeal reaction may have been related to the proximity of the cerebral lesions to the ventricles, a phenomenon previously described in non SLE related cerebral infarcts.
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