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Naproxen induced ulcerative esophagitis.
1Division of Rheumatology, Ottawa General Hospital, University of Ottawa, Ontario, Canada.
The Journal of Rheumatology
|April 1, 1992
Summary
Nonsteroidal anti-inflammatory drug (NSAID) use can cause ulcerative esophagitis, a rare cause of upper gastrointestinal bleeding in the elderly. This case highlights the importance of considering NSAIDs in older patients with esophageal issues.
Area of Science:
- Gastroenterology
- Internal Medicine
- Geriatrics
Background:
- Upper gastrointestinal bleeding (UGIB) is a common emergency in the elderly.
- Ulcerative esophagitis accounts for only 4% of UGIB cases in this population.
- Nonsteroidal anti-inflammatory drug (NSAID)-related esophageal bleeding is infrequently reported.
Observation:
- A case of an 87-year-old woman presenting with symptoms of upper gastrointestinal bleeding.
- The patient had a history of documented esophageal dysmotility.
- Esophageal ulceration was identified as the source of bleeding.
Findings:
- The ulcerative esophagitis was determined to be induced by nonsteroidal anti-inflammatory drug (NSAID) use.
- This represents a rare instance of NSAID-induced esophageal bleeding.
- Esophageal dysmotility may have contributed to the development of NSAID-induced ulcerative esophagitis.
Implications:
- Clinicians should consider NSAID-induced ulcerative esophagitis in elderly patients with UGIB, especially those with pre-existing esophageal motility disorders.
- NSAID use should be carefully evaluated in older adults presenting with esophageal symptoms or bleeding.
- This case underscores the potential gastrointestinal toxicity of NSAIDs in a vulnerable elderly population.