[Systemic immunologic diseases]

The systemic manifestation of immunological diseases is due to the spread of antigen mostly bound to specific antibody. Vasculitis and serositis follow the deposition of immune complexes to membranes. Whereas heterologous antigen causes temporary immune reactions, autologous antigen induces chronically reactions with definite destruction of tissue. Therefore, immunosuppression is indicated in autoaggressive diseases with rapid progrediency. In temporary reactions, however, antiphlogistic drugs and corticosteroids are sufficient.