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A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Malignant hypertension secondary to cortisol-secreting adrenal tumour
Shao-Wen Weng1, Cheng-Hsu Yang, Wan-Ting Huang
1Division of Endocrinology, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Abstract:
Adrenal cortical tumour-induced malignant hypertension is rare, except for some documented aldosterone-producing adenomas. Hypertension is a common feature of Cushing's syndrome, whereas malignant hypertension is rarely seen. This case in Taiwan is only the second reported case with malignant hypertension secondary to a cortisol-secreting adrenal tumour. The immunohistochemical study of the excised tumour showed strong positive staining of interleukin (IL)-6. IL-6 can trigger inflammatory vascular damage, which is typical in the malignant phase of hypertension. We hypothesise that IL-6 may have played an important role in this case.
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