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Updated: Aug 17, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Antimicrobial terpenoids from Pterocarpus indicus
Consolacion Y Ragasa1, Roderick D De Luna, Joy G Hofilena
1Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines. sagasac@dlsu.edu.ph
Abstract:
A mixture of loliolide 1 (> 85%) and paniculatadiol 2 (< 15%) was obtained from the ethyl acetate leaf extract of Pterocarpus indicus by silica gel chromatography, while the air-dried flowers afforded lupeol 3 and phytol esters 4. The structures of 1-4 were determined by NMR spectroscopy. Antimicrobial tests on a mixture of 1 and 2 indicated that it has moderate activity against Candida albicans and low activity against Pseudomonas aeruginosa, Escherichia coli, and Aspergillus niger. It was found inactive against Staphylococcus aureus, Bacillus subtilis, and Trichophyton mentagrophytes.
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