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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jul 1, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
12:06

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Published on: May 12, 2011

[Transnasal optic nerve decompression for optic nerve injury].

Hongping Zhang1, Daliang Zhang, Xuemei Chen

  • 1Department of Otorhinolaryngology, the Second Hospital of Shandong University, Jinan, 250033, China. tydzhp@sohu.com

Lin Chuang Er Bi Yan Hou Ke Za Zhi = Journal of Clinical Otorhinolaryngology
|June 9, 2005
PubMed
Summary

Intranasal endoscopic surgery effectively treats optic nerve injuries, with earlier intervention yielding better visual recovery. This minimally invasive technique offers significant advantages for patients with indirect optic neuropathy.

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Area of Science:

  • Ophthalmology
  • Neurosurgery
  • Endoscopic Surgery

Context:

  • Indirect optic neuropathy often results from trauma.
  • Surgical decompression is a primary treatment for optic nerve injury.
  • Intranasal endoscopic surgery is an emerging technique for optic nerve decompression.

Purpose:

  • To evaluate the feasibility, techniques, and benefits of intranasal endoscopic surgery for optic nerve injury.
  • To assess visual improvement rates following endoscopic optic nerve decompression.

Summary:

  • A retrospective study analyzed 39 cases (40 optic nerves) of indirect optic neuropathy treated with intranasal endoscopic surgery.
  • The transethmoidal or trans-sphenoid approach was used, decompressing the optic nerve within 2-18 days post-trauma.
  • A 60% overall effective rate of visual improvement was observed, with higher rates for surgery within 2-7 days (66.7%) compared to 8-18 days (30%).

Impact:

  • Intranasal endoscopic surgery provides excellent visualization and avoids complications associated with other approaches.
  • This technique offers a promising option for visual recovery in optic nerve injury.
  • The study suggests expanding indications for endoscopic optic nerve decompression.