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Aptamer-directed self-assembly of protein arrays on a DNA nanostructure

Yan Liu1, Chenxiang Lin, Hanying Li

  • 1Department of Chemistry and Biochemistry & Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

Angewandte Chemie (International Ed. in English)
|June 10, 2005
PubMed
Abstract

No abstract available in PubMed .

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...