Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Stereotactic radiotherapy for multiple brain metastases].

Huo-Sheng Xia1, Shou-Yun Han, Ping Li

  • 1Department of Radiotherapy, The 309th Clinical Division, Chinese PLA General Hospital, Beijing 100091, P. R. China. 309h@sina.com

AI Zheng = Aizheng = Chinese Journal of Cancer
|June 11, 2005
PubMed
Summary

Stereotactic radiotherapy (SRT) significantly improved outcomes for patients with multiple brain metastases compared to conventional radiotherapy. SRT led to higher effective rates, longer survival, and reduced recurrence.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiotherapy of unicentric mediastinal Castleman's disease.

Chinese journal of cancer·2011
Same author

Mercury exposure in the population from Wuchuan mercury mining area, Guizhou, China.

The Science of the total environment·2008
Same author

Swelling characteristics and drug delivery properties of nifedipine-loaded pH sensitive alginate-chitosan hydrogel beads.

Journal of biomedical materials research. Part B, Applied biomaterials·2008
Same author

Autoantibody profiling of Chinese patients with autoimmune hepatitis using immunoproteomic analysis.

Journal of proteome research·2008
Same author

Phenotypic characterization, genetic analysis, and molecular mapping of a new mutant gene for male sterility in rice.

Genome·2008
Same author

Human exposure to methylmercury through rice intake in mercury mining areas, Guizhou province, China.

Environmental science & technology·2008

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Context:

  • Multiple intracranial tumors present a therapeutic challenge.
  • Stereotactic radiotherapy (SRT) offers precise radiation delivery.
  • Limited data exists on SRT for multiple brain metastases.

Purpose:

  • To evaluate the efficacy and application of SRT in patients with multiple brain metastases.
  • To compare SRT outcomes with conventional radiotherapy (CR).

Summary:

  • A retrospective review of 136 patients with multiple brain metastases treated between 1996-2002.
  • 52 patients received CR, while 84 received SRT (alone or with WBRT).
  • SRT demonstrated significantly higher clinical effective rates (96.4% vs 86.5%) and elimination rates for larger metastases (>20 mm) (70.4% vs 36.0%) compared to CR.

Related Experiment Videos

Impact:

  • SRT significantly improved median survival time (10.5 vs 6.5 months) and 1-year survival rates (40.5% vs 21.2%).
  • SRT showed comparable rates of persistent brain edema and intracranial tumor recurrence to CR.
  • SRT is a valuable treatment option for improving quality of life and survival in patients with multiple brain metastases.