Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell motility as persistent random motion: theories from experiments.

David Selmeczi1, Stephan Mosler, Peter H Hagedorn

  • 1Danish Polymer Centre, and Biosystems Department, Risø National Laboratory, Roskilde, Denmark.

Biophysical Journal
|June 14, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Robotic manipulations of single cells using a large-volume piezoelectric micropipette with nanoliter precision" [Colloid. Surf. B Biointerfaces 256 (2025) 114972].

Colloids and surfaces. B, Biointerfaces·2025
Same author

Robotic manipulations of single cells using a large-volume piezoelectric micropipette with nanoliter precision.

Colloids and surfaces. B, Biointerfaces·2025
Same author

Calibrating photomultiplier tubes beyond their performance envelope.

The Review of scientific instruments·2025
Same author

Assessing Hybridization-Dependent Off-Target Risk for Therapeutic Oligonucleotides: Updated Industry Recommendations.

Nucleic acid therapeutics·2025
Same author

Direct Visualization of Defect-Controlled Diffusion in van der Waals Gaps.

Advanced materials (Deerfield Beach, Fla.)·2024
Same author

3D microperfusion of mesoscale human microphysiological liver models improves functionality and recapitulates hepatic zonation.

Acta biomaterialia·2023

Researchers developed cell-specific motility models from trajectory data. These models reveal cell memory and aid in distinguishing surface compatibility for human keratinocytes and fibroblasts.

Area of Science:

  • Cell biology
  • Biophysics
  • Quantitative biology

Background:

  • Cell migration is crucial for biological processes.
  • Analyzing cell trajectory data can reveal complex behaviors.
  • Human keratinocytes and fibroblasts have distinct physiological roles.

Purpose of the Study:

  • To develop cell-type-specific motility models.
  • To investigate the concept of cell memory in migration.
  • To establish quantitative methods for assessing surface-cell interactions.

Main Methods:

  • Experimental time series analysis of cell trajectories.
  • Development of mathematical models for cell motility.
  • Comparative analysis of human keratinocyte and fibroblast migration patterns.

Related Experiment Videos

Main Results:

  • Generated distinct motility models for keratinocytes and fibroblasts.
  • Demonstrated that cells possess a 'memory' of past velocities.
  • Identified quantitative parameters for evaluating surface compatibility.

Conclusions:

  • Cell trajectory data can yield predictive motility models.
  • Cellular memory influences migration dynamics.
  • Quantitative models can guide the selection of biomaterials for specific cell types.