[Circulatory system in twin to twin transfusion syndrome]

Twin to Twin Transfusion Syndrome (TTTS) is a common and severe complication of monochorionic twin pregnancies associated with high perinatal loss rates and significant morbidity and morality in the surviving neonate. In recent years substantial progress has been made in understanding the pathogenesis, in the early diagnosis and methods of TTTS treatment, but many controversies still exist. Dynamic advance in the therapy of this foetal pathology considerably limited the morality: enlarging the number of neonates and children who require multidisciplinary intensive care.

The purpose of this study was to evaluate the circulatory system lesions in TITS during foetal life, after birth and in long term follow up.

We reviewed the available information on TTTS with special attention focused on circulatory system pathophysiology.

A variety of cardiac system lesions seen in TTTS patients, many doubts and controversies concerning its aetiology and outcome create the necessity for further investigations including detailed circulatory system evaluation in the foetal life as well as in the neonatal period and long term follow-up.